Creative Atrophy: Creativity Science • UConn / James Kaufman

Creative Atrophy

What happens to human creativity when AI begins doing more of the thinking for us?

In this episode of UnNatural Selection, Nic Encina sits down with renowned creativity researcher James Kaufman to explore the psychology of innovation, the Four-C Model of Creativity, and the evolving relationship between human creativity and artificial intelligence.

Together, they unpack why creativity is one of humanity’s most democratic traits, why organizations struggle to foster innovation at scale, and how psychological safety, experimentation, and openness shape both corporate and societal evolution.

The conversation also dives into the risks of over-reliance on AI, the future of creative work, the hidden value of failure and persistence, and why societies that stop developing creative thinkers may eventually stagnate.

From education and neuroscience to corporate strategy and societal evolution, this episode examines creativity not as a luxury — but as a survival mechanism.

Nic Encina

Global Leader in Precision Health & Digital Innovation • Founder of World-Renown Newborn Sequencing Consortium • Harvard School of Public Health Chief Science & Technology Officer • Pioneer in Digital Health Startups & Fortune 500 Innovation Labs

https://www.linkedin.com/in/encina
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Funding the Frontier: Health AI Investing • Scientia Ventures / Harry Glorikian